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Although methandrostenolon differs from boldenone only by alkylation on the 17th carbon, its side effects are much stronger, especially at doses of 20-30 mg daily. Although its susceptibility to aromatize is weaker than that of testosterone, the resulting estrogen 17a-methylestradiol is much more potent than estradiol. Water retention and high blood pressure are therefore quite common, and already at low doses. Taking Clomid or Nolvadex during the cycle minimizes these effects. Methandrostenolon is also 17-alpha alkylated compound, which is quite toxic to the liver. Increase in liver function values occurs at doses above 10 mg per day. Although the use of methandrostenolone is generally associated with positive feelings of good cheer, at high dose (over 50 mg) it may result in an increase in aggression.