Drugs such as Nolvedex bind to the oestrogen receptors , therefore reducing the effects of the heightened oestrogen in the body. Such drugs do nothing to reduce the amount of oestrogen in the body; they merely reduce its effects via competition for the receptors . If the user wishes to reduce the amount of oestrogen they should look to drugs such as proviron and anastrozole , which are known as anti-aromatases - . they lower the conversion of the steroid to oestrogen and therefore reduces the overall amount of oestrogen present.
Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .
Many advanced users stack several compounds in order to get maximum results from their cycle. Normally when your stacking these types of products its best to use single compounds instead of premixed stacks. The problem with using a premixed stack is you may get more of one compound than you want. Most of these products have sweet spots. Lets use h-drol for an example according to many of the forums out there 75mg is the sweet spot for this compound. Now lets say you have a halodrol product that is mixed with 10mg of Methylstenbolone. In order to get the proper amount of hdrol you will get more than the recommended dose of M-sten.