As with cholesterol, eating too much of the wrong kinds of fats will raise your blood triglycerides. Therefore, it’s important to restrict the amounts of saturated fats and trans fats you allow into your diet. Triglyceride levels can also shoot up after eating foods that are high in carbohydrates or after drinking alcohol. That’s why triglyceride blood tests require an overnight fast. If you have elevated triglycerides, it’s especially important to avoid sugary and refined carbohydrates, including sugar, honey, and other sweeteners, soda and other sugary drinks, candy, baked goods, and anything made with white (refined or enriched) flour, including white bread, rolls, cereals, buns, pastries, regular pasta, and white rice. You’ll also want to limit dried fruit and fruit juice since they’re dense in simple sugar. All of these low–quality carbs cause a sudden rise in insulin, which may lead to a spike in triglycerides.
In the intestine , following the secretion of lipases and bile , triglycerides are split into monoacylglycerol and free fatty acids in a process called lipolysis . They are subsequently moved to absorptive enterocyte cells lining the intestines. The triglycerides are rebuilt in the enterocytes from their fragments and packaged together with cholesterol and proteins to form chylomicrons . These are excreted from the cells and collected by the lymph system and transported to the large vessels near the heart before being mixed into the blood. Various tissues can capture the chylomicrons, releasing the triglycerides to be used as a source of energy. Liver cells can synthesize and store triglycerides. When the body requires fatty acids as an energy source, the hormone glucagon signals the breakdown of the triglycerides by hormone-sensitive lipase to release free fatty acids. As the brain cannot utilize fatty acids as an energy source (unless converted to a ketone ), [ citation needed ] the glycerol component of triglycerides can be converted into glucose , via gluconeogenesis by conversion into dihydroxyacetone phosphate and then into glyceraldehyde 3-phosphate , for brain fuel when it is broken down. Fat cells may also be broken down for that reason, if the brain's needs ever outweigh the body's.
Most triglycerides are found in fat (adipose) tissue, but some triglycerides circulate in the blood to provide fuel for muscles to work. After a person eats, an increased level of triglycerides is found in the blood as the body converts the energy not needed right away into fat. Triglycerides move via the blood from the gut to adipose tissue for storage. In between meals, triglycerides are released from fat tissue to be used as an energy source for the body. Most triglycerides are carried in the blood by lipoproteins called very low-density lipoproteins (VLDL) .