All anabolic steroids exhibit negative cholesterol profile changes in the body to varying extent (some exhibit this more and some less). These changes involve the reduction of HDL (the good cholesterol) and increases of LDL (the bad cholesterol). The result of such changes involves an increased risk of arteriosclerosis, and the degree to which these changes occur for the worse are usually dose-dependent (with higher doses increasing the negative changes and the risks). Other factors that affect these negative cholesterol changes are: duration of use, and route of administration. This is where oral anabolic steroids hold a negative reputation for exhibiting a far worse negative impact on cholesterol in comparison to injectable anabolic steroids. This is because the liver serves to function as the cholesterol processing center for the human body, and the increased hepatotoxicity associated with anabolic steroids will result in even worse negative cholesterol changes.
Anabolic steroids are synthetic hormonal substances that behave like testosterone. They help build skeletal muscles (anabolic effect) and develop male characteristics (the androgenic effect). In fact, the exact name for these is anabolic-androgenic steroids. Doctors prescribe these for people with testosterone deficiency or with low red blood cell count. They are also used to treat adolescents experiencing delayed puberty or patients with breast cancer, aside from treating tissue wasting among people AIDS. 1 They must also not be confused with corticosteroids, a cortisone-like steroidal medication that controls inflammation and is used to treat a range of health problems.