How it works: According to Dr. Edwards, stress produces chemicals in the body that increase inflammation. “With relaxation techniques, you have stress reduction and therefore decreased inflammation and less pain,” she says. Meditation also relaxes muscles that tense up with pain. Dr. Edwards suggests meditating for 20 minutes once or twice a day. For moments of acute pain, she also recommends “meditation minutes.” For example, take four to five deep breaths, counting to 10 with each inhalation and exhalation. “Just doing that four to five times a day can decrease depression and improve outlook,” she says.
Bufotoxins are a family of toxic steroid lactones . They occur in the parotoid glands , skin and poison of many toads ( genus Bufo ) and other amphibians, and in some plants and mushrooms.    The exact composition varies greatly with the specific source of the toxin. It can contain: 5-MeO-DMT , bufagins , bufalin , bufotalin , bufotenin , bufothionine , epinephrine , norepinephrine , and serotonin . The term bufotoxin can also be used specifically to describe the conjugate of a bufagin with suberylargine.