Hi, I have an agonizing sharp pain on the outside of my left leg, about 3" below the centre of the knee. It started hurting while jogging about 7 months ago, I 'd and then rested for about 6 weeks but the pain continued. I've had cortisone injections, anti inflammatories and pain killers but nothing has seemed to help. I'm under an orthopedic consultant but they are scratching their heads. My x rays and ultrascan are both clear and I'm worried they'll discharge me without ever getting to the root of the problem.
Slow release NSAIDs dissolve mostly in the small intestine, past the stomach, decreasing the chance of stomach upset - however, the gastrointestinal effects of these medications are not eliminated. NSAIDs decrease inflammation by decreasing prostaglandins (natural substances involved in inflammation) and certain prostaglandins are required to protect the stomach lining from stomach acid. Some NSAIDs have less severe gastrointestinal side effects than others because they have less effect on the stomach prostaglandins (. Cox-II Selective Inhibitors)
This is exactly what happened to me. I had perfectly healthy 18 year old cartilage in my 50s. I went to my orthopedic doctor for a patellar tracking problem in both knees that could be corrected with simple exercise. But in the meantime my doctor gave me many cortisone injections. 2 years later I was bone on bone. I was and am still absolutely horrified as I have no knee damage history. I became a cripple overnight. I pursued legal action against the drug company who makes the cortisone but it couldn’t be proven unfortunately. Regenexx has helped tremendously to get my life back! I am back to hiking 3 days a week. Thank you Regenexx. You are a God send!!